产品货号：
Z10404
中文名称：
ACVR1C抗体
英文名称：
Anti-ACVR1C Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ACVR1C Antibody |
| 指标别名 | activin A receptor;type IB;Activin receptor like kinase 4;Activin receptor type 1B;Activin receptor type IB;ACTR IB;ACTRIB;ACVR1B;ACVRLK4;ALK 4;ALK4;SKR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | ACVR1C |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ACVR1C antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ACVR1C.The immunogen is located within amino acids 130 - 180 of ACVR1C. |
| 计算分子量 | 57kDa |
| 成分 | ACVR1C Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ACVR1C Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors.ACVR1C,also known as ALK7,is a type I activin receptor and plays a role in cell differentiation,growth arrest and apoptosis.ACVR1C can mediate signaling by ligans such as Nodal,GDF-1/3,activin B and activin AB,all of which can also signal through the ubiquitous activin type I receptor ACVR1B (also known as ALK4).ACVR1C is a novel marker specifically expressed during the late phase of adipocyte differentiation.ACVR1C is dispensable for mouse embryogenesis,which suggests alternative functions for this receptor in postnatal development and tissue homeostasis.ACVR1C plays an important role in regulating the functional plasticity of pancreatic islets,negatively affecting beta-cell function by mediating the effects of activin B on Ca2+ signaling. |
| Uniprot ID | Q8NER5 |
| 基因名全称 | Activin A receptor,type I |
| 蛋白名全称 | Activin A receptor,type I |
| 推荐稀释比 | ACVR1C antibody can be used for detection of ACVR1C by Western blot at 1 and 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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